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Invasion of new adaptive zones retains telltale signs of directional selection at macroevolutionary scales in mammals
Directional selection is often viewed as a transient force in macroevolution, with its signal eroded over time by stabilizing and …
Fabio A. Machado, Anna Penna, Diogo Melo, Barbara A. Costa, Thiago M. G. Zahn, Ana C. Pavan, Arthur Porto, Harley Sebastião, Daniela M. Rossoni, Gabriel Marroig, Alex Hubbe
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Invasion of new adaptive zones retains telltale signs of directional selection at macroevolutionary scales in mammals
Bumble bee workers adopt new roles and reshape social networks after queen loss
Dominant individuals often structure group organization, but less is known about how social networks reorganize in their absence and …
Dee M. Ruttenberg, Scott Wolf, Andrew E. Webb, Eli S. Wyman, Michelle L. White, Diogo Melo, Ian M. Traniello, Sarah D. Kocher
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Bumble bee workers adopt new roles and reshape social networks after queen loss
Saturating the eQTL map in Drosophila: Genome-wide patterns of cis and trans regulation of transcriptional variation in outbred populations
Most genetic polymorphisms associated with complex traits are found in non-coding regions of the genome. Characterizing their effect …
Luisa F. Pallares, Diogo Melo, Scott Wolf, Evan M. Cofer, Varada Abhyankar, Julie Peng, Julien F. Ayroles
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Saturating the eQTL map in Drosophila: Genome-wide patterns of cis and trans regulation of transcriptional variation in outbred populations
Longitudinal sequencing reveals polygenic and epistatic nature of genomic response to selection
Evolutionary adaptation to new environments likely results from a combination of selective sweeps and polygenic shifts, depending on …
Simon K. G. Forsberg, Diogo Melo, Scott W. Wolf, Jennifer K. Grenier, Minjia Tang, Lucas P. Henry, Luisa F. Pallares, Andrew G. Clark, Julien F. Ayroles
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Longitudinal sequencing reveals polygenic and epistatic nature of genomic response to selection
Disentangling variational bias: the roles of development, mutation, and selection
The extraordinary diversity and adaptive fit of organisms to their environment depends fundamentally on the availability of variation. …
Haoran Cai, Diogo Melo, David L. Des Marais
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Disentangling variational bias: the roles of development, mutation, and selection
Reassessing the modularity of gene co-expression networks using the Stochastic Block Model
Finding communities in gene co-expression networks is a common first step toward extracting biological insight from such complex …
Diogo Melo, Luisa F. Pallares, Julien F. Ayroles
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Reassessing the modularity of gene co-expression networks using the Stochastic Block Model
Morphological integration during postnatal ontogeny: implications for evolutionary biology
How covariance patterns of phenotypes change during development is fundamental for a broader understanding of evolution. There is …
Alex Hubbe, Fabio A. Machado, Diogo Melo, Guilherme Garcia, Harley Sebastião, Arthur Porto, James Cheverud, Gabriel Marroig
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Morphological integration during postnatal ontogeny: implications for evolutionary biology
Measuring the Magnitude of Morphological Integration: The Effect of Differences in Morphometric Representations and the Inclusion of Size
The magnitude of morphological integration is a major aspect of multivariate evolution, providing a simple measure of the intensity of …
Fabio A. Machado, Alex Hubbe, Diogo Melo, Artur Porto, Gabriel Marroig
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Measuring the Magnitude of Morphological Integration: The Effect of Differences in Morphometric Representations and the Inclusion of Size
Genomic Perspective on Multivariate Variation, Pleiotropy, and Evolution
Multivariate quantitative genetics provides a powerful framework for understanding patterns and processes of phenotypic evolution. …
Diogo Melo, Gabriel Marroig, Jason B. Wolf
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Genomic Perspective on Multivariate Variation, Pleiotropy, and Evolution
The Evolution of Phenotypic Integration: How Directional Selection Reshapes Covariation in Mice
Variation is the basis for evolution, and understanding how variation can evolve is a central question in biology. In complex …
Anna Penna, Diogo Melo, Sandra Bernardi, Maria Inés Oyarzabal, Gabriel Marroig
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The Evolution of Phenotypic Integration: How Directional Selection Reshapes Covariation in Mice